Fast, accurate and reliable results aid medical professionals to understand the illness and develop the strategy for an effective treatment. It is the responsibility of the medical device manufacturer and the person placing the medical device on the market to ensure compliance of the medical device with all applicable laws and regulations, including the suitability of all raw materials and components used for its manufacture.

sa=i&rct=j&q=&esrc=s&frm=1&source=images&cd=&cad=rja&uact=8&ved=0CAcQjRw&url=http://www.mullerquaker.com/products/greek100/greek100-peach-and-passion-fruit&ei=-acYVZq7EIqwyASDjYL4CA&bvm=bv.89381419,d.cWc&psig=AFQjCNGNCQY1_dCN2RPLzxtap_Pu0omTXQ&ust=1427765484498432 POLYONE CORPORATION 25 2015 Revenue: $0.7 Billion At a Glance: Performance Products & Solutions 2015 Revenue by Industry Expanding Profits 5.5% 6.9% 3.8% 3.6% 5.5% 4.3% 6.3% 7.2% 7.7% 8.3% 12-14% 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 YTD 2020 Operating Income % of Sales Platinum Vision 11.6% B & C 31% Transportation 19% W & C 16% Industrial 13% Appliances 7% Consumer 5% Packaging 5% E & E 3% Healthcare 1% United States 79% Canada 14% Latin America 5% Asia 2% Key Applications POLYONE CORPORATION 26 2015 Revenue: $1.0 Billion At a Glance: Distribution Key Suppliers ROIC Expanding Profits 2.6% 3.0% 3.5% 4.0% 4.6% 5.6% 6.4% 5.9% 6.1% 6.6% 6.5-7.5% 6.6% 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 YTD 2020 Operating Income % of Sales Platinum Vision 15% 53% 2006 3Q 2016 Transportation 24% Healthcare 23% Industrial 16% Consumer 13% E & E 6% Appliances 6% W & C 4% Packaging 4% B & C 4% http://www.polyone.com/Pages/VariationRoot.aspx 27 POLYONE CORPORATION Application Examples POLYONE CORPORATION 28 Luxury Packaging with Gravitech Density Modified Polymers  Impart weight, sound and metallic finish to caps and closures for cosmetics and spirits applications  Elevate quality and prestige perceptions among high-end consumers  Eliminate time and cost associated with secondary operations and assembly POLYONE CORPORATION 29 Medical Device Housings with Chemically Resistant Engineered Polymers  Durable, long-lasting products stand up to the most aggressive disinfectants  Minimize environmental stress cracking and discoloration  One of the broadest medically approved polymer and colorant portfolios POLYONE CORPORATION 30 Printed Circuit Boards with Thermally Conductive Polymers  Replaces metal by etching circuit designs into thermally conductive plastic  Maintains heat transfer and cooling capabilities of metals  Reduces both weight and cost  Increases the lifetime and reliability of electronic systems POLYONE CORPORATION 31 Color & Design Services  Greater control of color development and supply chain  Work across entire design process from concept to commercialization  Inspire creativity in the use of polymer materials, colors and effects  Innovative brand differentiation  Faster development timelines POLYONE CORPORATION 32 Outdoor Applications  Leading provider of high performance specialty materials for the recreational and sports & leisure industry  Well positioned across all segments to address market needs  Metal to Polymer Conversion  Lightweighting  Thermal Management  Impact Performance Source: Outdoor Industry Association POLYONE CORPORATION 33 Fiber Colorants Solutions for clothing, apparel, footwear, automotive & sporting goods  ColorMatrix Fiber Colorant Solutions  Proprietary advanced liquid color formulations and equipment enable greater efficiency and productivity  Eliminates aqueous dyeing and its associated wastewater treatment  Solid Color Concentrates  Extrusion-spun fibers colored via solid masterbatch POLYONE CORPORATION 34  Improve performance and reduce cost through light-weighting, reduced waste, faster cycle times and extended shelf life  Aligned with megatrend of facing climate and resource challenges:  Sustainability benefits include lower package weight and improved recyclability of package at end of use Shelf-life extension Greater product consistency Recyclability and reduced carbon footprint Color and Special Effects Weight reduction Enhanced product aesthetics High heat resistance Preservative Technology POLYONE CORPORATION 35 Metal Replacement Solutions  Replaces metal in LED lighting  Extends LED durability and life span eliminating hot spots  Greater design flexibility with fewer parts  Weight reduction  Simplifies manufacturing and lowers total production cost POLYONE CORPORATION 36 High-Barrier Packaging Containers  Capability to extrude up to 13 layers  Strong oxygen and moisture vapor transmission protection  Can be made symmetrical or asymmetrical to meet customized needs of broad variety of applications  Barrier protection and superior sensory properties 1 Reconciliation of Non-GAAP Financial Measures (Unaudited) (Dollars in millions, except per share data) Below is a reconciliation of non-GAAP financial measures to the most directly comparable measures calculated and presented in accordance with U.S. Segment Highlights At a Glance: Color, Additives & Inks At a Glance: Specialty Engineered Materials At a Glance: Designed Structures & Solutions At a Glance: Performance Products & Solutions At a Glance: Distribution Application Examples Luxury Packaging�with Gravitech Density Modified Polymers Medical Device Housings�with Chemically Resistant Engineered Polymers Printed Circuit Boards�with Thermally Conductive Polymers Color & Design Services Outdoor Applications Fiber Colorants�Solutions for clothing, apparel, footwear, automotive & sporting goods Slide Number 34 Metal Replacement Solutions High-Barrier Packaging Containers

sa=i&rct=j&q=&esrc=s&frm=1&source=images&cd=&cad=rja&uact=8&ved=0CAcQjRw&url=http://www.mullerquaker.com/products/greek100/greek100-peach-and-passion-fruit&ei=-acYVZq7EIqwyASDjYL4CA&bvm=bv.89381419,d.cWc&psig=AFQjCNGNCQY1_dCN2RPLzxtap_Pu0omTXQ&ust=1427765484498432 POLYONE CORPORATION 25 2015 Revenue: $0.7 Billion At a Glance: Performance Products & Solutions 2015 Revenue by Industry Expanding Profits 5.5% 6.9% 3.8% 3.6% 5.5% 4.3% 6.3% 7.2% 7.7% 8.3% 12-14% 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 YTD 2020 Operating Income % of Sales Platinum Vision 11.6% B & C 31% Transportation 19% W & C 16% Industrial 13% Appliances 7% Consumer 5% Packaging 5% E & E 3% Healthcare 1% United States 79% Canada 14% Latin America 5% Asia 2% Key Applications POLYONE CORPORATION 26 2015 Revenue: $1.0 Billion At a Glance: Distribution Key Suppliers ROIC Expanding Profits 2.6% 3.0% 3.5% 4.0% 4.6% 5.6% 6.4% 5.9% 6.1% 6.6% 6.5-7.5% 6.6% 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 YTD 2020 Operating Income % of Sales Platinum Vision 15% 53% 2006 3Q 2016 Transportation 24% Healthcare 23% Industrial 16% Consumer 13% E & E 6% Appliances 6% W & C 4% Packaging 4% B & C 4% http://www.polyone.com/Pages/VariationRoot.aspx 27 POLYONE CORPORATION Application Examples POLYONE CORPORATION 28 Luxury Packaging with Gravitech Density Modified Polymers  Impart weight, sound and metallic finish to caps and closures for cosmetics and spirits applications  Elevate quality and prestige perceptions among high-end consumers  Eliminate time and cost associated with secondary operations and assembly POLYONE CORPORATION 29 Medical Device Housings with Chemically Resistant Engineered Polymers  Durable, long-lasting products stand up to the most aggressive disinfectants  Minimize environmental stress cracking and discoloration  One of the broadest medically approved polymer and colorant portfolios POLYONE CORPORATION 30 Printed Circuit Boards with Thermally Conductive Polymers  Replaces metal by etching circuit designs into thermally conductive plastic  Maintains heat transfer and cooling capabilities of metals  Reduces both weight and cost  Increases the lifetime and reliability of electronic systems POLYONE CORPORATION 31 Color & Design Services  Greater control of color development and supply chain  Work across entire design process from concept to commercialization  Inspire creativity in the use of polymer materials, colors and effects  Innovative brand differentiation  Faster development timelines POLYONE CORPORATION 32 Outdoor Applications  Leading provider of high performance specialty materials for the recreational and sports & leisure industry  Well positioned across all segments to address market needs  Metal to Polymer Conversion  Lightweighting  Thermal Management  Impact Performance Source: Outdoor Industry Association POLYONE CORPORATION 33 Fiber Colorants Solutions for clothing, apparel, footwear, automotive & sporting goods  ColorMatrix Fiber Colorant Solutions  Proprietary advanced liquid color formulations and equipment enable greater efficiency and productivity  Eliminates aqueous dyeing and its associated wastewater treatment  Solid Color Concentrates  Extrusion-spun fibers colored via solid masterbatch POLYONE CORPORATION 34  Improve performance and reduce cost through light-weighting, reduced waste, faster cycle times and extended shelf life  Aligned with megatrend of facing climate and resource challenges:  Sustainability benefits include lower package weight and improved recyclability of package at end of use Shelf-life extension Greater product consistency Recyclability and reduced carbon footprint Color and Special Effects Weight reduction Enhanced product aesthetics High heat resistance Preservative Technology POLYONE CORPORATION 35 Metal Replacement Solutions  Replaces metal in LED lighting  Extends LED durability and life span eliminating hot spots  Greater design flexibility with fewer parts  Weight reduction  Simplifies manufacturing and lowers total production cost POLYONE CORPORATION 36 High-Barrier Packaging Containers  Capability to extrude up to 13 layers  Strong oxygen and moisture vapor transmission protection  Can be made symmetrical or asymmetrical to meet customized needs of broad variety of applications  Barrier protection and superior sensory properties 1 Reconciliation of Non-GAAP Financial Measures (Unaudited) (Dollars in millions, except per share data) Below is a reconciliation of non-GAAP financial measures to the most directly comparable measures calculated and presented in accordance with U.S. Segment Highlights At a Glance: Color, Additives & Inks At a Glance: Specialty Engineered Materials At a Glance: Designed Structures & Solutions At a Glance: Performance Products & Solutions At a Glance: Distribution Application Examples Luxury Packaging�with Gravitech Density Modified Polymers Medical Device Housings�with Chemically Resistant Engineered Polymers Printed Circuit Boards�with Thermally Conductive Polymers Color & Design Services Outdoor Applications Fiber Colorants�Solutions for clothing, apparel, footwear, automotive & sporting goods Slide Number 34 Metal Replacement Solutions High-Barrier Packaging Containers Investor Presentation - November 2016 r4 (2).pdf Investor Presentation - November 2016

Various materials and their resistnace to common disinfectants used in consumer, industrial, and medical applications  

Various materials and their resistnace to common disinfectants used in consumer, industrial, and medical applications  

Various materials and their resistnace to common disinfectants used in consumer, industrial, and medical applications  

Various materials and their resistnace to common disinfectants used in consumer, industrial, and medical applications  

MEDICAL TUBING EXTRUDER B I O P H A R M A C E U T I C A L T U B I N G • Low leachables & extractables • Great tensile performance and kink resistance • Good thermal weldability • Excellent clarity and medical blue tint • ISO 10993-4 & 5, USP Class VI & Animal Derivative Free (ADF) • Supplied drop-in material replacement to overcome supply constraints of incumbent TPE • Offered a lower extractable profile than comparable materials in the market • Enabled easy material transition without changes in tooling or thermal welding machine settings • Formulated solution with proprietary additives to provide clarity and prevent yellowing after sterilization Versaflex™ HC BT218 Thermoplastic Elastomer KEY REQUIREMENTS WHY AVIENT?

240625-2017-AQ-RGC-NA-PS Initial certification date: 14 September 2017 Valid: 08 February 2025 – 07 February 2028 This is to certify that the management system of PolyOne-Shanghai, China 88 Guoshoujing Road, Z.J.Hi-Tech Park, Pudong Shanghai, China (Unicode: 91310000607342402D) has been found to conform to the Quality Management System standard: ISO 13485:2016 This certificate is valid for the following scope: Design, Manufacture, Sales and Distribution of Medical Colour and Additive Concentrates Used for the Plastic Parts of Medical Devices http://www.dnv.com

MEDICAL DEVICE MANUFACTURER S T E T H O S C O P E S • Provide a silicone paste colorant dispersion for liquid silicone rubber (LSR) to use in stethoscope ear tips • Create a custom-colored vinyl plastisol formulation for stethoscope tubing • Harmonize color across materials to meet specific process and performance requirements • Deliver effective communication and cross-functional collaboration • Offered dependable silicone paste colorants that allowed for comfort and easy sterilization • Provided a colored vinyl plastisol to reduce tackiness and support product longevity • Collaborated internally to align all materials and provide color consistency across components • Supported fast color changes and met quality specifications through constant communication and technical expertise Silcopas Silicone Paste Colorants and CORE Vinyl Plastisols for Healthcare KEY REQUIREMENTS WHY AVIENT? https://www.avient.com/products/vinyl-formulations/vinyl-plastisols-organosols/core-vinyl-plastisols-healthcare https://www.avient.com/products/polymer-colorants/colorant-dispersions/colorants-liquid-silicone-rubber Slide 1: Medical device manufacturer