https://www.avient.com/sites/default/files/2021-10/microbial-susceptibility-of-various-polymers-and-evaluation.pdf
This renewed awareness for
Received: 27 April 2021 Revised: 29 July 2021 Accepted: 21 September 2021
DOI: 10.1002/pen.25815
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided
the original work is properly cited
To reduce the incidence of device-associated infections,
antimicrobial technologies have been utilized in a variety
of ways ranging from bulk-imbedded additives to sur-
face grafting techniques.[13,14] In particular, silver-based
additive technologies are frequently explored for
healthcare applications due to their favorable toxicological
profiles and broader regulatory approvals, while silver
nanoparticles with controlled, long-term release profiles
continue to be a very active and promising area of biomedi-
cal research.[15-19] In textile segments such as sports active-
wear, biocides are used to prevent the growth of odor-
causing bacteria from perspiration.[20,21] Additionally,
high-end recreational products such as boats utilize bio-
cides to preserve the aesthetics of PVC products used for
seat covers since bacterial growth may lead to pink staining
caused by specific bacterial metabolites.[22,23] With respect
to the mechanism of action, many antimicrobial products
work by attacking enzymes common to a variety of
microbes, interfering with membrane transport processes
(e.g., importing environmental copper into the cells) as
well as interfering with iron metabolism pathways.[24,25]
Herein, an assortment of both rigid and flexible resins/
compounds will be evaluated for susceptibility to determine
whether particular resin chemistries or compounds are
inherently vulnerable to microbial growth and subsequent
degradation or other deleterious effects.