CATEGORY DETAIL EC Number 215-175-0 CAS Number 1309-64-4 Name Subclass 1 Antimony Trioxide (ATO) Structural Formula CHEMICAL IDENTITY PROPERTY DETAIL Physical State Solid Form Powder Color White Odor Odorless Melting Point 656°C Boiling Point 1425°C Bulk Density 5.20 g/cm3 Water Solubility Slightly Soluble PHYSICAL/ CHEMICAL PROPERTIES HEALTH EFFECTS HUMAN HEALTH SAFETY ASSESSMENT Consumer It is very unlikely that consumers would be exposed to ATO in its concentrated form because it is only sold for industrial use to make polymers and other products and is not sold directly to consumers.

Verwendung des Produkts oder (ii) der Einhaltung oder Nichteinhaltung von Gesetzen und Vorschriften auf Bundes-, Landes-, Provinz- oder Kommunalebene ergeben, die diese Aktivitäten regeln oder kontrollieren. Buyer shall be exclusively responsible for (i) ensuring compliance with all Laws and Standards associated with its intended use of Product; and (ii) obtaining all necessary approvals, permits or clearances for such use. Buyer shall be exclusively responsible for (i) ensuring compliance with all Laws and Standards associated with its intended use of Product; and (ii) obtaining all necessary approvals, permits or clearances for such use.

Unless expressly stated to the contrary, prices are (i) fixed and firm (ii) exclusive of any Value Added Tax (“VAT”) but (iii) inclusive of all other taxes, duties, levies, fees (including license fees), labeling, packaging, shipping, charges and inclusive all costs. 3.2 Avient shall pay the amount invoiced by Supplier by bank transfer as follows: 3.2.1 North America. Avient shall not be responsible for delayed payments in case invoices are sent by Supplier after the period under (ii) above. 3.5 Unless otherwise agreed between the Parties, Supplier will execute the purchasing process (including but not limited to the Purchase Order, order confirmation, shipping notification, invoicing) through electronic communication. 4. Avient is entitled to reject any Goods, which are delivered (i) not at the agreed time, (ii) not in the agreed volume and/or quantity, (iii) in inappropriate or damaged packaging or (iv) with other defect(s), for risk and account of Supplier and without prejudice to Avient's right to compensation for the losses and damages suffered as a result of Supplier’s non- compliance. 6.

KEY CHARACTERISTICS • Available for polyethylene, polypropylene, ABS, polycarbonate and styrenics • Bio-content of resin carrier varies from 70% to 100% depending on polymer—calculated to ASTM D6866 standard • Manufactured at four ISO 13485 certified sites, providing global consistency and security of supply • Documented change control beyond CAS number, reducing risk of change • Drop-in solutions that can be processed like fossil-based grades on common injection molding and extrusion machines • Can be provided as ready-to-use pre-colored or additive formulation REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 - USP and (incl. class VI) - European Pharmacopeia, monograph 3.1.3/ 3.1.5 (polyolefin packaging materials) - USP (polyethylene) - Elemental impurities as per ICH Q3D • Registered Drug Master File (Type III) and/or Device Master File • Food contact according to US FDA and APPLICATION BULLETIN Sustainability Spotlight Bio-polymers Healthcare use limitations apply—see below.

REGULATORY SUPPORT • Drug delivery devices • Pharmaceutical packaging • Medical equipment KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing the risk of change • Allows crystallization in semi-crystalline polymers to begin faster and complete earlier REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing risk of change • Non-phthalate and formulated without animal-derived substances • Different tones of amber available on request —more or less red or yellow and/or lighter or darker • Also available in liquid form REGULATORY SUPPORT • Pre-tested raw materials: - ISO 10993-1 and USP parts (Class VI) - European Pharmacopeia, monograph 3.1.15, USP and elemental analysis as per ICH Q3D - USP criteria appearance of solution, color • Registered Drug Master File (Type III) by the FDA • Food contact compliance established with FDA/EU* • YBB00102002-2015 (oral liquid pharmaceutical PET bottles) compliance support APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

Any form of discrimination in violation of the provisions of Title VII of the Civil Rights Act of 1964, as amended, Title I and Title V of the Americans with Disabilities Act of 1990, as amended, The Age Discrimination in Employment Act of 1967, as amended, and/or Title II of the Genetic Information Nondiscrimination Act of 2008, or this policy is against the interests of Avient and its employees and will not be permitted.

Any form of discrimination in violation of the provisions of Title VII of the Civil Rights Act of 1964, as amended, Title I and Title V of the Americans with Disabilities Act of 1990, as amended, The Age Discrimination in Employment Act of 1967, as amended, and/or Title II of the Genetic Information Nondiscrimination Act of 2008, or this policy is against the interests of Avient and its employees and will not be permitted.

II GOLD PEARL II MI DRIFTWOOD II