MEVOPUR Colors for Ophthalmic Closures Application Bulletin_CN8.18-1 * 可根据要求提供FDA/EU合规信息 应用公告 用于眼科药物容器盖的 着色剂MEVOPUR™ 用于眼部（眼科）用药物容器盖的MEVOPUR标 准母粒系列产品符合美国眼科学会（AAO）的颜 色标准。

PHARMACEUTICAL PACKAGING OEM V I A L S , B O T T L E S & C O N T A I N E R S • Raw materials pre-tested to USP 661.1 and ICHQ3D guidelines • Stabilization during molding and sterilization processes for both opaque and transparent polymer materials • Certified formulations available globally • Offered pre-tested raw materials and produced in an ISO 13485 certified site, minimizing risk across the pharmaceutical value chain • Delivered specialized formulated solutions to meet stringent pharmaceutical packaging requirements • Provided global formulations transferrable from our three ISO 13485 certified facilities Mevopur™ Healthcare Concentrates KEY REQUIREMENTS WHY AVIENT? AVIENT SOLUTION CERTIFICATION + AVAILABILITY LEARN MORE © 2021, Avient Corporation, All Rights Reserved https://www.avient.com/products/polymer-colorants/solid-color-masterbatches/mevopur-custom-colors-and-formulations

Mevopur™ Healthcare Bio-based Polymer Solutions Mevopur™ Healthcare Functional Additives Mevopur™ Healthcare Functional Additives

Mevopur colorants can be used for various needs, such as brand recognition and differentiation, drug identification, and visual appeal. Likewise, Mevopur functional additives can help to protect or enhance the performance of polymers used in medical devices, diagnostics, or pharmaceutical packaging. The Mevopur product line also includes color and additive concentrates based on polymers with 70%-100% bio-content and pre-tested raw materials which can help to reduce carbon footprint and offer alternatives to fossil-based grades.

LABORATORY EQUIPMENT MANUFACTURER P C R W E L L P L A T E S • Very high level of TiO2 to prevent “cross-talk” between the wells during the qPCR fluorescence testing procedure • Minimized background phosphorescence caused by agglomeration of TiO2 and/or oxidized (stressed) polystyrene • Preservation of polystyrene grade properties • Change control of formulation and manufacturing process • Robust product quality from batch to batch • Developed optimally dispersed, ready-to-use white formulation that maintains adequate signal transmission, as well as minimizing “cross-talk” and background phosphorescence • Optimized the use of general purpose polystyrene (GPPS) for a good balance between melt flow and other physical properties, such as stiffness • Provided comprehensive change control of raw materials and formulation, with a robust manufacturing process and quality control under a third party ISO 13485:2016 certified QMS Mevopur Healthcare Colorants and Formulations – pre-colored solution WHY AVIENT? All Rights Reserved. https://www.avient.com/products/polymer-colorants/healthcare-colorants/mevopur-healthcare-colorants-and-formulations Slide 1: laboratory equipment manufacturer

NAME COLOR FAMILY COLOR CODE TRANSPARENTS Transparent Blue Violet Violet PPT6730-4005 Transparent Aquamarine Blue PPT6730-5018 Transparent Teal Green Green PPT6730-564C Transparent Optimal Yellow Yellow PPT6730-458C Transparent Energy Orange Orange PPT6730-150C Transparent Crimson Red PPT6730-2009 Transparent True Gray Gray PPT6730-7001 OPAQUES Linen White White PPO6730-9010 Hygienic White White PPO6730-9001 Ice Gray Gray PPO6730-5C True Gray Gray PPO6730-424C Shadow Gray PPO6730-446C Gunmetal Gray PPO6730-426C Black Black PPO6730-6C Powder Blue Blue PPO6730-2127C Smoky Blue Blue PPO6730-7682C Bright Azure Blue PPO6730-653C Cobalt Blue PPO6730-5002 Navy Blue PPO6730-5004 Aquamarine Blue PPO6730-7699C Blue Violet Violet PPO6730-7456C Emerald Green PPO6730-6016 Clover Green PPO6730-7723C Optimal Yellow Yellow PPO6730-459C Energy Orange Orange PPO6730-2000 Crimson Red PPO6730-3000 Colors may vary from actual color shown. NAME COLOR FAMILY COLOR CODE OPAQUES Marigold Yellow RPO6750-1006 Lime Yellow Green RPO6750-389C Royal Blue Blue RPO6750-5005 Mist Gray Gray RPO6750-7035 Overcast Gray RPO6750-7042 Deep Charcoal Black RPO6750-9004 Storm Gray Gray RPO6750-7015 Tin Gray RPO6750-7004 Tangerine Orange RPO6750-2004 Ginger Orange RPO6750-2000 Manilla White RPO6750-1013 Pine Green Green RPO6750-6029 Sea Green Green RPO6750-3262 Indigo Violet RPO6750-7668C Nut Brown Brown RPO6750-8008 Chocolate Brown RPO6750-8017 Chili Pepper Red RPO6750-3000 1.844.4AVIENT www.avient.com Copyright © 2023, Avient Corporation.

MEVOPUR Colors and Additives for IVD Devices Application Bulletin_CN 应用公告 应用于体外诊断医疗器械的 颜色和功能性添加剂MEVOPUR™ 目前诊断设备和耗材在提供安全治疗方面，与从 前相比，发挥着更为重要的作用。

MEVOPUR Bio-based Solutions Application Bulletin_JP_1.18-1 MEVOPUR™ バイオベースポリマーソリューション 医療機器・医薬品包装用 サステナビリティ バイオポリマー 製品紹介 医療機器や医薬品包装の製品開発にも、サステ ナビリティを考慮する必要性が高まっていま す。

MATERIAL BREAKTHROUGH: VERSAFLEX™ CE BLUE JEAN STAIN RESISTANT TPES FOR WHITE OR LIGHT-COLORED PHONE CASES Phone case brands have struggled to design white or light-colored cases that do not stain when in contact with blue jeans. Avient has formulated a new material that offers blue jean stain resistance similar to that of silicone*, yet with all the benefits of using a TPE: increased design freedom, an efficient supply chain leading to faster speed to market, and lower total part costs. A section of blue jeans was cut and the seam opened.

Avient has developed the approach of “Controlled, Consistent, Compliant” for our MEVOPUR™ and REMAFIN-EP™ products, designed specifically for healthcare applications. Fingerprinting and routine batch testing of the raw materials used in MEVOPUR and REMAFIN-EP help detect changes and implement countermeasures.