Mevopur™ Healthcare Colorants and Formulations Amber Colorants for Pharmaceutical Packaging Avient constantly monitors the evolution of regulations in the healthcare industry, and develops compliant products well before those regulations go into effect. Mevopur Healthcare Colorants and Formulations in amber tones provide the safety of pre-tested raw materials while protecting and prolonging the shelf life of pharmaceuticals and nutraceuticals in amber PET packaging products. KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing risk of change • Non-phthalate and formulated without animal-derived substances • Different tones of amber available on request —more or less red or yellow and/or lighter or darker • Also available in liquid form REGULATORY SUPPORT • Pre-tested raw materials: - ISO 10993-1 and USP parts (Class VI) - European Pharmacopeia, monograph 3.1.15, USP and elemental analysis as per ICH Q3D - USP criteria appearance of solution, color • Registered Drug Master File (Type III) by the FDA • Food contact compliance established with FDA/EU* • YBB00102002-2015 (oral liquid pharmaceutical PET bottles) compliance support APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

Mevopur™ Healthcare Colorants and Formulations Special Effect Colorants for Healthcare Devices and Pharmaceutical Packaging Self-administered medication, for example via pen devices and inhalers, has been the norm for many years. Ingredients used in the Mevopur™ portfolio have been tested to industry standards that support applications in both medical devices and pharmaceutical packaging.* KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified manufacturing sites, providing global consistency and increased security of supply • Documented change control beyond CAS number, reducing risk of change • Non-phthalate and formulated without animal-derived substances • Available as pre-colored formulation or concentrate and for use in different polymers REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU** APPLICATION BULLETIN * Design note: Effect colors require careful consideration of part design and polymer flow paths to minimize visible flow lines.

We can give you design flexibility with both liquid and solid colorants to make your products pop.

Certificate of Amendment Loi canadienne sur les sociétés par actionsCanada Business Corporations Act Certificat de modification Avient Colorants Canada Inc. 942266-8 Corporate name / Dénomination sociale Corporation number / Numéro de société Raymond Edwards Date of amendment (YYYY-MM-DD) Date de modification (AAAA-MM-JJ) Director / Directeur 2021-01-15 I HEREBY CERTIFY that the articles of the above-named corporation are amended under section 178 of the Canada Business Corporations Act as set out in the attached articles of amendment. Corporation number Numéro de la société 2 942266-8 The articles are amended as follows Les statuts sont modifiés de la façon suivante 3 The corporation changes its name to: La dénomination sociale est modifiée pour : Avient Colorants Canada Inc.

Mevopur™ Healthcare Bio-Based Polymer Solutions are color and performance-enhancing additive solutions formulated with bio-based polymers for healthcare applications. Remafin™ EP White Colorants for Pharmaceutical Packaging designed for a range of pharmaceuticals, safeguarding light transmission while meeting regulatory requirements.

in 2011 as assistant controller, a position he held until being named director of finance for the company's Color, Additives and Inks business segment.  He joined the company in 2010 and has since advanced through progressively increasing roles of global responsibility, including external reporting manager; assistant corporate controller; finance director for Color, Additives and Inks; and finance director for

Color and Additives Solutions Overview Colorant and additives overview and capabilities

Avient has developed a "Heat Stability Protocol" to screen new additive solutions for their impact on color and NIAS through two full recycle loops at 100% recycled content. This provides minimal effect on color shift and product safety.

Backed by robust bio-compatibility pre-testing, healthcare quality systems, and change control standards, these ‘medical grade’ concentrates and pre-color formulations can help minimize risk and avoid high costs of non-compliance. Mevopur™ Custom Colors and Formulations

With colors that are on-trend and inspiring. Color Cosmetics