Rev1 This certificate’s validity is subject to the organization maintaining their system in accordance with ABS Quality Evaluations, Inc. 1701 City Plaza Dr Spring, TX 77389 USA requirements for management system certification. Rev1 This certificate’s validity is subject to the organization maintaining their system in accordance with ABS Quality Evaluations, Inc. 1701 City Plaza Dr Spring, TX 77389 USA requirements for management system certification. Rev1 This certificate’s validity is subject to the organization maintaining their system in accordance with ABS Quality Evaluations, Inc. 1701 City Plaza Dr Spring, TX 77389 USA requirements for management system certification.

USP Class VI and ISO 10993-4/5 compliant ASTM ISO Shore A/D ASTM/ISO %

Like other Mevopur products, they are formulated with raw materials tested to ISO 10993-1 and USP , European Pharmacopeia 3.1.3 and 3.1.5, USP and ICH Q3D.   Certified for USP Class VI and ISO 10993, the new Versaflex HC BIO BT218 grade is commercially available globally. Versaflex™ HC Thermoplastic Elastomers series HC3810: translucent TPE formulations offering excellent colorability for injection molded parts and over-molding, developed to comply with ISO 10993-4 and -5, REACH SVHC, and RoHS

Standard colors for use in needle hubs (ISO 6009) Global network of ISO 13485 certified manufacturing sites ISO 6009 color range

Schematic representation of creep mechanism; chain alignment and void formation in response to applied stress. 3© 2021 Avient Corporation, 33587 Walker Road, Avon Lake, Ohio USA 44012 There are several key factors which can influence the timeline to ESC failure: 1. MATERIAL BRIEF DESCRIPTION FR PC/ABS Flame retardant, chemical resistance, high ESCR FR PC/PET Flame retardant, impact modified, chemical resistant FR PC/PBT Skin-contact biocompatible, flame retardant, high chemical resistance FR Copolyester Flame retardant, chemical resistant, may incorporate agency-rated materials to meet USP Class VI or ISO 10993 requirements Trilliant™ HC8910 Unfilled PK blend, BPA-free, high chemical resistance, may incorporate agency-rated materials to meet USP Class VI or ISO 10993 requirements Trilliant™ HC8920 FR Non-halogenated flame retardant PK blend, BPA-free, high chemical resistance, may incorporate agency rated materials to meet USP Class VI or ISO 10993 requirements Edgetek™ ET8900 CR Unfilled PK blend, high chemical resistance Edgetek™ ET8900 HI CR High impact PK blend, high chemical resistance Edgetek™ ET8920 FR CR Non-halogenated flame retardant PK blend, high chemical resistance Table 2. - - 8© 2021 Avient Corporation, 33587 Walker Road, Avon Lake, Ohio USA 44012 Table 3B.

Avient Colorants USA LLC Avient Colorants USA LLC

The company is headquartered in Kingsport, Tennessee, USA, and employs approximately 15,000 people around the world.

9279-H-61 CERT.

CX-6180-B CERT.

Version / Date: 1 (no adjustments) / 30.12.2024 Page 1 of 2 ISCC PLUS Certificate Certificate Number: ISCC-PLUS-Cert-PL214-26100824 Bureau Veritas Polska Sp. z o.o. Version / Date: 1 (no adjustments) / 30.12.2024 Page 2 of 2 Annex I to the certificate: Sustainable materials handled by the certified site (This annex is applicable for all scopes except of Trader, Trader with storage, Warehouse, Logistic centres, MTBE and ETBE) This annex is only valid in connection with the certificate: ISCC-PLUS-Cert-PL214-26100824 issued on 30.12.2024 Input material Output material Add-ons (voluntary)1) Raw material category2) SAI FSA3) FEFAC4) Polypropylene (PP) Plastic Compounds (PP) NO Bio Bio-circular Circular N/A N/A Polyethylene (PE) Plastic Compounds (PE) NO Bio Bio-circular Circular N/A N/A 1) ISCC PLUS add-ons (voluntary application, see www.iscc-system.org for further information): • 202-04: Food Security Standard • 205-02: Consumables • 202-07: Low ILUC-risk feedstock • 205-03: Non GMO for food and feed • 205-01: GHG emission requirements • 205-04: Non GMO for technical markets 2) Bio raw materials complies with the ISCC Principles 1 – 6 for the cultivation and harvesting of sustainable biomass.